You can build your own Frankenstein guitar like Eddie Van Halen. This is not so difficult today. I will show you my idea on how it can be done from the electronics wiring side.
My wiring is designed for use with a Stratocaster style guitar.
I'm suggesting a Strat, because it's a very comfortable guitar for modifications. It has got easy to change pick-guard and electronics. Many on-line stores are selling parts for these instruments.
The market has got a lot of Squiers and other, economical constructions stylized on famous Fender. You can also use some MIM Strat or even Warmoth parts.
My wiring design is based on one pickup: single-coil sized humbucker (or full size for Fat-Strat). The circuit is quite original - it's not a copy of the Frankenstein. It has got three signal controllers: volume control, tone switch and killswitch. I think, that they can be very useful for fans of shredding and heavy rhythms.
Diagram:
